Parkinson’s disease is a progressive neurological disorder. The first signs are problems with movement. Smooth and coordinated muscle movements of the body are made possible by a substance in the brain called dopamine. Dopamine is produced in a part of the brain called the “substantia nigra.” In Parkinson’s, the cells of the substantia nigra start to die. When this happens, dopamine levels are reduced. When they have dropped 60 to 80 percent, symptoms of Parkinson’s start to appear. Symptoms of Parkinson’s disease: Some of the early symptoms of Parkinson’s can come before motor problems by several years. These earliest signs include: decreased ability to smell (anosmia) constipation small, cramped handwriting voice changes stooped posture The four major motor problems seen are: tremor (shaking that occurs at rest) slow movements stiffness of arms, legs, and trunk problems with balance and tendency to fall Secondary symptoms include: blank facial expression a tendency to get stuck when ...
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